SPIRHR Research Update
Research capacity building is a cornerstone of SPIRHR’s mission, achieved through specialized trainings, workshops, and the provision of grants.
Below is an updated list of research projects, both published and ongoing, that have received direct financial or technical support from SPIRHR’s annual research seed grant. This grant is designed to empower researchers by promoting a hands-on, “learning by doing”; approach. The projects are led by faculty members from the Department of Obstetrics and Gynecology, working in collaboration with colleagues from various departments within the college, fostering a multidisciplinary approach to research and innovation.
| S.N | Title of the research project | Principal investigator | Status |
|---|---|---|---|
| 1 | Tufa, Tesfaye Hurissa, Sarah Prager, Mekitie Wondafrash, Shikur Mohammed, Nicole Byl, and Jason Bell. "Comparison of surgical versus medical termination of pregnancy between 13-20 weeks of gestation in Ethiopia: A quasi-experimental study." Plos one 16, no. 4 (2021): e0249529. | Dr Tesfaye Hurrisa | https://pubmed.ncbi.nlm.nih.gov/33793655/ |
| 2 | Abubeker, Ferid A., Biruck Gashawbeza, Thomas Mekuria Gebre, Mekitie Wondafrash, Alula M. Teklu, Demis Degu, and Delayehu Bekele. "Analysis of cesarean section rates using Robson ten group classification system in a tertiary teaching hospital, Addis Ababa, Ethiopia: a cross-sectional study." BMC pregnancy and childbirth 20 (2020): 1-7. | Dr Ferid Abas | https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-020-03474-x |
| 3 | Sium, Abraham Fessehaye, Tesfaye H. Tufa, Jaclyn M. Grentzer, and Sarah Prager. "Effectiveness of intra-cardiac lidocaine and intra-amniotic digoxin at inducing fetal demise before second trimester abortion past 20 weeks at a tertiary Hospital in Ethiopia: A retrospective review." Contraception: X 4 (2022): 100082. | Dr Abraham Fessehaye | https://doi.org/10.1016/j.conx.2022.100082 |
| 4 | Gudu, W*., Wondafrash, M., Bekele, D., Nigatu, B., Barrera, M., et al. (2022) The Impact of Covid-19 Pandemicon Obstetrics and Gynecology Residency Programs and Perspectives on Adaptive Ways of Training in Ethiopia. Adv SexReprod Health Res, 1(1), 60-70 (PDF) Volume 1| Issue 1 | 60 Advances in Sexual & Reproductive Health Research. Available from: https://www.researchgate.net/publication/365991467_Volume_1_Issue_1_60_Advances_in_Sexual_Reproductive_Health_Research [accessed Nov 29 2024]. | Dr Wondimu Gudu | DOI: 10.33140/ASRHR |
| 5 | Belay, Lemi, Thomas Mekuria, and Mekitie Wondafrash. "In vitro fertilization (IVF) outcomes and predicting factors in a resource-limited setting." Ethiopian journal of reproductive health 13.03 (2021): 10-10. | Dr Thomas Mekuria | DOI: https://doi.org/10.69614/ejrh.v13i03.493 |
| 6 | Tolu LB, Tufa TH, Abas F, et al. Intra-cardiac lidocaine administration to induce fetal demise before late second-trimester abortion: Retrospective review. Int J Gynaecol Obstet. 2021;153(1):125-129. doi:10.1002/ijgo.13419 | Dr Lemi Belay | doi:10.1002/ijgo.13419 |
| 7 | PTeshome, A., Wondafrash, M., Gashawbeza, B., Nigatu, B., Asrat, M. and Compton, S.D. (2021), Post-abortion contraceptive adoption in Ethiopia. Int. J. Gynecol. Obstet., 154: 157-161. https://doi.org/10.1002/ijgo.13555 | Dr Abel Teshome | https://obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/ijgo.13555 |
| 8 | Tolu LB, Gudu W (2020) Sexual assault cases at a tertiary referral hospital in urban Ethiopia: One-year retrospective review. PLOS ONE 15(12): e0243377. https://doi.org/10.1371/journal.pone.0243377 | Dr Wondimu Gudu | https://journals.plos.org/plosone/article/authors?id=10.1371/journal.pone.0243377 |
| 9 | Asrat Shiferaw M, Grentzer JM, Wondafrash M, et al. Factors associated with contraceptive use among women with epilepsy: A cross-sectional study. Public Health Chall. 2024; 3:e188. https://doi.org/10.1002/puh2.188 | Dr Matiyas Asrat | https://onlinelibrary.wiley.com/doi/10.1002/puh2.188 |
| 10 | Bekele D, Asfaw M, Nigatu B, et al. A randomized controlled trial of sequential vs simultaneous use of Foley balloon catheter and oxytocin for induction of labor in nulliparous pregnant women. AJOG Glob Rep. 2023;3(3):100252. Published 2023 Aug 1. doi:10.1016/j.xagr.2023.100252 | Prof. Delayehu Bekele | https://pubmed.ncbi.nlm.nih.gov/37645648/ |
| 11 | Gudu W, Abdulkadir A, Wondafrash M. Introducing second-trimester anatomic scanning for improved detection and management of congenital anomalies: Experience from a novice center in East Africa. Int J Gynaecol Obstet. 2024;167(3):1237-1242. doi:10.1002/ijgo.15810 | Dr Wondimu Gudu | https://pubmed.ncbi.nlm.nih.gov/39031104/ |
| 12 | Bayable M, Gudu W, Wondafrash M, Sium AF. Incidence, indications, and maternal outcomes of emergency peripartum hysterectomy at a tertiary hospital in Ethiopia: A retrospective review. Int J Gynecol Obstet. 2023; 161: 279-282. doi: 10.1002/ijgo.14510 | Dr Mahri Bayable | doi: 10.1002/ijgo.14510 |
| 13 | Wondimu Gudu, Malede Birara, Mekitie Wondafrash et al. Cultural Competence among Health Care Providers at a Teaching Hospital in Ethiopia, 11 April 2024, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-4228802/v1] | Dr. Wondimu Gudu | https://www.researchsquare.com/article/rs-4228802/v1 |
| 14 | Gudu W, Sisay ZT, Wondafrash M, Sium AF (2023) Cesarean delivery surgical techniques in Africa: A survey study from Ethiopia. PLOS ONE 18(10): e0292382. https://doi.org/10.1371/journal.pone.0292382 | Dr Wondimu Gudu | https://doi.org/10.1371/journal.pone.0292382 |
| 15 | Bekele, D., Gudu, W., Wondafrash, M., Abdosh, A. A., & Sium, A. F. (2024). Utilization of third-trimester fetal transcerebellar diameter measurement for gestational age estimation: a comparative study using Bland-Altman analysis. AJOG Global Reports, 4(1), 100307. | Dr Delayehu Bekele | https://www.sciencedirect.com/science/article/pii/S2666577824000017?via%3Dihub |
| 16 | Mekuria T, Wondafrash M, Sium AF. Premature luteinization and pregnancy outcomes in depot goserelin-downregulated assisted reproductive technology cycles: A cross-sectional study from Ethiopia. Int J Gynecol Obstet. 2024; 00: 1-5. doi:10.1002/ijgo.15503 | Dr Thomas Mekuria | https://obgyn.onlinelibrary.wiley.com/doi/10.1002/ijgo.15503# |
| 17 | Birara M, Urgie T, Sium AF (2024) Locally advanced cervical cancer: Neoadjuvant chemotherapy plus radical surgery an alternative approach to chemo-radiation in a low-income setting: A descriptive study. PLOS ONE 19(10): e0310457. https://doi.org/10.1371/journal.pone.0310457 | Dr Tadesse Urgie | https://doi.org/10.1371/journal.pone.0310457 |
| 18 | Ansa, M., Negash, M., Wondafrash, M. ., & Teshome, A. . (2024). Prevalence and predictors of ovarian hyper stimulation syndrome at Center fertility and repro-ductive medicine at Public IVF center, Ethiopia. Ethiopian Journal of Reproductive Health, 16(1). https://doi.org/10.69614/ejrh.v16i1.733 | Dr Meseret Ansa | DOI: https://doi.org/10.69614/ejrh.v16i1.733 |
| 19 | Mahtemsilassie, M., Wondafrash, M., Negash, M., & Ansa, M. . (2023). Biochemical Pregnancy Outcomes among Day 3 Vs 5 Embryotransfer in the Fertility Reproductive Mecicine Center at Teritary Hospital, Addis Ababa, Ethiopia. Ethiopian Journal of Reproductive Health, 15(2). https://doi.org/10.69614/ejrh.v15i2.640 | Dr Mintesnot Mahtemsilassie | https://doi.org/10.69614/ejrh.v15i2.640 |
| 20 | Birara, M., Urgie, T. ., & Fessehaye Sium, A. . (2024). Gynecololgic Cancers at a Tertiary Hospital at Teritiery Hospital in AddisAbaba, Ethiopia. A 5 years Review. Ethiopian Journal of Reproductive Health, 16(1). https://doi.org/10.69614/ejrh.v16i1.743 | Dr Tadesse Urgie | https://doi.org/10.69614/ejrh.v16i1.743 |
| 21 | Sium AF, Shimeles T, Gudu W. The effect of induced fetal demise on induction to expulsion interval during later medication abortion: A retrospective cohort. Contraception. 2023;125:110092. doi:10.1016/j.contraception.2023.110092 | Dr Abraham Fessehaye | doi:10.1016/j.contraception.2023.110092 |
| 22 | Sium AF, Tolu LB, Wolderufael M, Tufa T, A. Abubeker F, Prager S. Second-trimester dilatation and evacuation: Comparison of routine intraoperative ultrasonography versus problem-based intraoperative ultrasonography in reducing procedure-related complications: A pre-post study. Int J Gynecol Obstet. 2024; 165: 1182-1188. doi:10.1002/ijgo.15328 | Dr Abraham Fessehaye | doi:10.1002/ijgo.15328 |
| 23 | Fessehaye Sium A, Lucero-Prisno DE III, Wondafrash M, Tolu LB, Asrat Shiferaw M. Late request for safe abortion care at a tertiary hospital in Ethiopia; the role of emotional factors: A cross-sectional study. Int J Gynecol Obstet. 2022; 158: 462–468. doi:10.1002/ijgo.14065. | Dr Matiyas Asrat | doi:10.1002/ijgo.14065. |
| 24 | GuduW, Bekele D, Surur F, Tekulu A, Abesha Y, Negatu B, Kass M, Lako T, Sium AF, The role of male partner in women’s fertility decision and family planning utilization in four regional states of Ethiopia: A mixed method study. Int J Gynaecol Obstet. 2023 June 2023 DOI: 10.1002/ijgo.14973 | Dr Wondimu Gudu | DOI: 10.1002/ijgo.14973 |
| 25 | Sium AF, Gudu W, Tolu LB, Birara M, Bekele D. Missed opportunity for aspirin prophylaxis for preeclampsia prevention: a cross-sectional study from Sub-Saharan Africa. AJOG Glob Rep. 2023;4(1):100295. Published 2023 Dec 4. doi:10.1016/j.xagr.2023.100295 | Prof. Delayehu Bekele | doi:10.1016/j.xagr.2023.100295 |
| 26 | Sium AF, Lucero-Prisno DEIII, Gudu W. Perinatal outcomes of twin pregnancies complicated with preeclampsia at a tertiary hospital in Ethiopia: A case-control study. Public Health Chall. 2022; 1:e37. https://doi.org/10.1002/puh2.37 | Dr Abraham Fessehaye | https://onlinelibrary.wiley.com/doi/10.1002/puh2.37 |
| 27 | Sium, Abraham Fessehaye, Abrham Getachew, and Wondimu Gudu. "Pre-referral management of preeclampsia with severity features in a low-income country—characteristics and challenges in a Sub-Saharan setting: a mixed method study." AJOG Global Reports 4.3 (2024): 100379. | Prof. Delayehu Bekele | https://doi.org/10.1016/j.xagr.2024.100379 |
| 28 | Bekele D, Gudu W, Tolu LB, Birara M, Sium AF. Preeclampsia prevention: a survey study on knowledge and practice among prenatal care providers in Ethiopia. AJOG Glob Rep. 2023 Dec 30;4(1):100300. doi: 10.1016/j.xagr.2023.100300. PMID: 38318266; PMCID: PMC10839527. | Prof. Delayehu Bekele | doi: 10.1016/j.xagr.2023.100300 |
| 29 | Lemma K, Bekele D, Tolu LB, Tadesse F, Kifle T, Sium AF. Birth companionship: The effect of introducing Plan-Do-Study-Act (PDSA) intervention on improving quality of care: An implementation study. Int J Gynecol Obstet. 2024; 00: 1-3. doi:10.1002/ijgo.15863” | Dr Kidist Lemma | doi:10.1002/ijgo.15863 |
| 30 | Shimels T, Gashaw B, Gedif T (2022) Association between delayed initiation of treatment indications and survival in patients with cervical cancer: A systematic review and meta-analysis protocol. PLOS ONE 17(7): e0271604. https://doi.org/10.1371/journal.pone.0271604 | Tariku Shimelis | https://doi.org/10.1371/journal.pone.0271604 |
| 31 | Tariku Shimels, Biruck Gashawbeza, Teferi Gedif Fenta. Association between delayed initiation of treatment indications and survival in patients with cervical cancer: a systematic review and meta-analysis. European Journal of Gynaecological Oncology. 2024. 45(3);4-15. | Tariku Shimelis | https://www.ejgo.net/articles/10.22514/ejgo.2024.043 |
| 32 | Shimels T, Gashawbeza B, Fenta TG (2024) Validation of the Amharic version of perceived access to healthcare services for patients with cervical cancer in Ethiopia: A second-order confirmatory factor analysis. PLOS ONE 19(5): e0300815. https://doi.org/10.1371/journal.pone.0300815 | Tariku Shimelis | https://doi.org/10.1371/journal.pone.0300815 |
| 33 | Shimels T, Gashawbeza B, Gedif Fenta T. Access to advanced healthcare services and its associated factors among patients with cervical cancer in Addis Ababa, Ethiopia. Front Oncol. 2024;14:1342236. Published 2024 Feb 23. doi:10.3389/fonc.2024.1342236 | Tariku Shimelis | DOI: 10.3389/fonc.2024.1342236 |
| 34 | Sium, A.F., Gudu, W., Getachew, A. et al. South-to-south collaboration: advancing quality of abortion care through health care professionals exchange program. BMC Health Serv Res 25, 120 (2025). https://doi.org/10.1186/s12913-025-12225-7 | Dr Abraham Fessehaye | https://doi.org/10.1186/s12913-025-12225-7 |
| 35 | Sium, A. F., Prager, S., & Reeves, M. (2025). Patient acceptability of intra-amniotic digoxin versus intracardiac lidocaine for inducing foetal demise prior to second trimester medical abortion: a prospective cohort. The European Journal of Contraception & Reproductive Health Care, 1–4. https://doi.org/10.1080/13625187.2024.2444237 | Dr Abraham Fessehaye | https://doi.org/10.1080/13625187.2024.2444237 |
| 36 | Sium AF, Kirba S, Tolu LB. Task-sharing: Abortion care access expansion through training midwives and nurses to provide first trimester abortion in a sub-Saharan setting: A multicenter pre-post study. Int J Gynecol Obstet. 2025; 00: 1-5. doi:10.1002/ijgo.16188 | Dr Abraham Fessehaye | https://doi.org/10.1002/ijgo.16188 |
| 37 | Fetal malnutrition status at birth using clinical assessment of nutritional status score and anthropometric indices and predictors of it among term newborns in Selected Public Hospitals of Addis Ababa | Aman Yusuf ( School of Public Health) | Data collection |
| 38 | Contraceptive Use and Associated Factors among High School Adolescents in Addis Ababa, Ethiopia | Dr Ferid Abas / Addisu Gize | Manuscript written |
| 39 | Recto-Vaginal and Neonatal Group B Streptococcus (GBS) Colonization among Laboring Mothers and their Newborns at a Referral Hospital in Addis Ababa, Ethiopia | Prof. Delayehu Bekele / Addisu Gize | Data collection |
| 40 | Survival of Patients taking NACT followed by Interval Debulking Surgery for Advanced Stage Ovarian Cancer in St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia | Dr Kidist Lemma | Data analysis |
| 41 | Sium AF, Gudu W, Getachew A, NTASUMBUMUYANGE D, Nithinyurwa P, Woldemichael TE, Bekele D. South to South collaboration: Advancing quality of abortion care through health care professionals exchange program. BMC Health Services Research. 2024 Dec. | Dr Abraham Fessehaye | Submitted for publication |
| 42 | Sium AF, Prager S, Reeves M. Patient acceptability of intra-amniotic digoxin versus intracardiac lidocaine for inducing fetal demise prior to second trimester medication abortion: a prospective cohort. The European Journal of Contraception & Reproductive Health Care. 2024 Dec. | Dr Abraham Fessehaye | Submitted for publication |
| 43 | Foley catheter versus laminaria for cervical preparation prior to second-trimester dilation and evacuation: Open-label a non-inferiority randomized trial | Dr Abraham Fessehaye | Registered as RCT with a reg number: PACTR202408852551318 ; Ongoing data collection |
| 44 | Epidemiology, Knowledge, Attitude, and Practice towards Viral Hepatitis among Pregnant Women attending Antenatal care in Addis Ababa, Ethiopia | Dr Aida Tilahun | Data collection completed |
| 45 | Perioperative morbidity and associated factors after gynecologic oncologic surgery at SPHMMC, Addis Ababa, Ethiopia, A three years audit at a tertiary hospital | Dr Biruck Gashawbeza | Data collection ongoing |
| 46 | Efficacy of medication abortion for late first-trimester pregnancy termination | Dr Kidist Lemma | Data collection ongoing |
| 47 | Placenta Accreta Syndrome: Incidence, prenatal diagnosis and Outcomes in developing countries. A 5 years Retrospective analysis at SPHMMC | Dr Malede Birara | Ongiong data collection |
| 48 | Acceptability of child adoption in the management of infertility: A survey of clients attending fertility clinic at a tertiary facility Addis Ababa, Ethiopia 2024 | Dr Selamawit Yihun | Ongiong data collection |
| 49 | Performance of Preeclampsia Prediction model among Pregnant Women attending Antenatal care at SPHMMC and catchment Health centers | Dr Wondimu Gudu | Ongoing |
| 50 | Self-assessment of gestational age for medical abortion | Dr Zerihun Beyene | Data analysis |
| 51 | Amioinfusion in low-income setting: it’s role in reducing CS burden and perinatal complications: a retrospective descriptive study | Dr Abraham Fessehaye | Manuscript submitted for publication |
| 52 | A Comparative Study on the Success Rates of In Vitro Fertilization (IVF) between Frozen and Fresh Embryo Transfer: Single Center Retrospective Cohort Study | Dr Ayalew Marye | Manuscript submitted for publication |
| 53 | Outcome of induction of labor versus expectant management in women with impending post-term pregnancy: A Randomized Controlled Clinical Trial | Dr Mariamawit Asfaw | Ethic approval process |
| 54 | Evaluating the Feasibility, Acceptability, and Outcomes of the E-MOTIVE Bundle Intervention for Postpartum Hemorrhage Management in Resource-Limited Settings: An Implementation Study in Ethiopia | Dr Wondimu Gudu | Data collection underway |